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Gynecomastia in men: symptoms, causes, treatment, and how to diagnose
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Reviewed by: Dr. Kimi Khan, Consultant Dermatologist

Gynecomastia is a medical condition that affects the breast tissue and causes it to become enlarged in males.

Gynecomastia in men 

Gynecomastia is a condition characterized by enlarged breast tissue in males, which can affect one or both breasts, and is often caused by a discrepancy in the levels of the hormones testosterone and estrogen. 

This condition is relatively common and can occur at different stages of life. The incidence in infants is estimated at between 60% and 90%, while in adolescents it reaches 60%. 

In men aged 50 to 69 years, the prevalence can be up to 70%. 

Understanding the causes, symptoms, and treatment options of gynecomastia is essential to effectively manage the condition and provide appropriate care.

Causes of gynecomastia in men

Hormonal disorders and imbalances in testosterone and estrogen levels are the main cause of the development of gynecomastia in men, as we mentioned.

Testosterone is the primary male hormone responsible for developing masculine traits, while estrogen is the primary female hormone. However, both hormones are found in the bodies of men and women in different proportions.

 When there is an excess of estrogen or a low level of testosterone, gynecomastia may develop in men.

Here are some common causes contributing to hormonal imbalance and gynecomastia in men:

  • Medications, which may include:
  • Psychiatric medications, including antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and lithium. 
  • Treatment medications Prostate diseasesA, such as finasteride and dutasteride, which men use for cases of benign prostatic hyperplasia, which may be a cause of gynecomastia, especially in men older than 50 years.
  • Steroid medications, which some athletes use to build muscle quickly.
  • Medicines used to treat weak fertility and infertility in men.
  • Chronic diseases, as some different health conditions may affect the growth and enlargement of breast tissue, including:
    • Hyper الغدة الدرقية, which affects the balance of other hormones indirectly.
    • Kidney or liver disease, as these conditions can interfere with the normal functioning of hormones.
    • Tumors, the most important of which are tumors of the testicle, adrenal gland, or pituitary gland, which affect, in one way or another, the production of hormones.
    • Cases of severe malnutrition, which disrupts the normal production of hormones.

Risk factors for gynecomastia in men

Some factors can also contribute to the development of gynecomastia, such as:

  • Obesity: The presence of excess fat in the body increases the production of estrogen, which leads to hormonal imbalance and the development of gynecomastia.
  • Excessive use of alcohol and some substances, such as marijuana or estrogen-stimulating seeds, and anabolic steroids.
  • Aging: As men age, testosterone levels naturally decrease while estrogen levels may remain constant or increase, contributing to the development of gynecomastia in some.

We know that breast growth in men may be a worrying matter for some, but it is important to note that gynecomastia is usually not caused by breast cancer. However, a specialist doctor must be consulted;

What are the degrees of gynecomastia in men? 

Gynecomastia in men is classified according to the severity of the enlargement into three degrees, as follows:

  •  Grade 1 (mild), the enlargement is small around the nipple without excess skin, and is only visible when touched or with wearing tight clothing. 
  • Grade 2 (moderate),  divided into A, which is a pronounced enlargement similar to adolescent breasts without sagging skin, or  B,  which is an enlargement with mild sagging of the skin.
  • Grade 3 (severe), presence of significant enlargement with obvious skin laxity resembling female breasts

Symptoms of gynecomastia in men

After we got to know the possible causes of the infection, we must know that there is a difference between gynecomastia and excess fat in men, and gynecomastia is characterized by some common symptoms, such as:

  • One or two breasts are enlarged, and feel sensitive or painful to the touch.
  • Imbalanced breast appearance: Enlargement may occur more in one breast than the other, resulting in an asymmetrical or disproportionate appearance of the breasts.
  • Changes in the nipple, becoming sensitive or painful, or turning inward, as a result of changes in the underlying breast tissue.

Gynecomastia also causes psychological stress, feelings of shame, and body image problems, leading to low self-confidence.

It is important to note that gynecomastia is usually a benign condition and does not cause severe pain or discomfort. However, if you are experiencing severe pain, rapid breast growth, leaking nipple discharge, or any other worrisome symptoms, you should seek medical help quickly.

How do you differentiate between gynecomastia and fat in men?

To differentiate between gynecomastia and fat in men, the following factors must be taken into account:

  • Gynecomastia appears firm, firm, and elastic, while chest fat is usually soft to the touch, similar to body fat in other areas.
  • Gynecomastia tends to be rounder and more symmetrical, while chest fat often appears saggy or droopy and has no distinct shape.
  • Chest fat responds to diet and exercise, while gynecomastia does not.
  • Gynecomastia may cause mild pain in the chest area, while chest fat is not a source of pain.
  • Gynecomastia may look like a hard lump just below the nipple, while breast fat usually does not cause any lumps.

If you are not sure why excess tissue appears in your chest, it is essential to consult a healthcare professional for an accurate diagnosis.

How is gynecomastia diagnosed?

If you suspect that you may be suffering from gynecomastia, it is important to see a specialist for a comprehensive evaluation, including:

  • Complete medical history, including knowledge of symptoms and accompanying medical conditions, in addition to the medications or nutritional supplements you take.
  • physical examination;
  • Blood tests, through which the doctor determines hormone levels, including testosterone and estrogen, to evaluate any hormonal disorder. 
  • Imaging tests, such as ultrasound or mammogram;

Accurate diagnosis and identification of the underlying cause of gynecomastia helps guide appropriate treatment options.

 What is the difference between true and false gynecomastia?

You can differentiate between true gynecomastia and false gynecomastia at home. Lie on your back and place your hands under the nipple. If you feel a hard lump (true glandular tissue) that resembles a coin, it is true gynecomastia, while if the texture is homogeneous like fat, it is false gynecomastia. 

This is because true gynecomastia results from the growth of true glandular tissue in a man’s breast due to a hormonal imbalance, and does not disappear with weight loss, while false gynecomastia results from the accumulation of fat only due to obesity or weight gain, and does not improve with weight loss.

What is the treatment for gynecomastia in men?

Treatment for gynecomastia in men depends on several factors, including the underlying cause, severity of symptoms, and their impact on the individual's quality of life.

  • Wait and watch: In many cases, gynecomastia in teens may resolve naturally without the need for medical intervention. Healthcare providers suggest a period of waiting and watching and allowing the breast tissue to naturally decline, after careful examination.
  • Medications: These medications aim to treat hormonal disorders and reduce breast tissue enlargement. These medications include:
  • Selective estrogen receptor modulators (SERMs): such as tamoxifen which may help block the effects of estrogen on breast tissue and reduce breast size.
  • Aromatase inhibitors: These medications, such as anastrozole and letrozole, work to inhibit the conversion of male hormones into estrogen, which reduces estrogen levels in the body.

Medications should be taken with caution and under the supervision of a specialist doctor, as they may have potential side effects and require careful monitoring.

Gynecomastia surgery for men

If gynecomastia persists and does not respond to the traditional treatments mentioned, surgical intervention may be the appropriate option along with drug treatment.

Gynecomastia surgery, also known as male breast reduction surgery, aims to correct enlarged male breast tissue and reshape the chest circumference.

  • Liposuction: This procedure aims to remove excess accumulations of fat through small incisions using suction technology.
  • Mastectomy: In more severe cases, it may require removing glandular breast tissue through surgery.

The decision to undergo surgery should be made after a consultation with a qualified plastic surgeon to evaluate the individual case and discuss the risks, benefits and expected results of the procedure.

The appearance of gynecomastia in men may be a challenge and affect the man’s psychological state, but it is important to remember that this condition is often the result of hormonal disorders and not serious tumor conditions, and there are many treatment options available, the most important of which are medications and surgery for severe or persistent cases. 

We hope that our article has provided you with valuable information and targeted advice for dealing with this situation. 

Frequently asked questions

What does gynecomastia in men indicate?

In general, gynecomastia in men does not necessarily indicate a serious health problem in all cases, but it may be an indicator of several things, the most prominent of which are:

  • Hormonal imbalance, which is the main cause of gynecomastia, occurs naturally during adolescence and old age. 
  • The presence of an underlying health condition that requires medical attention, as is the case with chronic kidney disease, kidney failure, and liver disease such as cirrhosis.
  • The presence of hypogonadism and testosterone production.
  • Hyperthyroidism, producing large amounts of the hormone thyroxine.
  • Some types of tumors, such as testicular tumors, adrenal gland tumors, or pituitary gland tumors. 
  • Side effects of taking some medications, such as anti-androgens, anabolic steroids, some heart medications, medications for treating ulcers and stomach ulcers, and some antidepressants and anti-anxiety agents.
  • Excessive alcohol consumption and drug abuse.

How do you know if you have gynecomastia or not?

To know if you are suffering from true gynecomastia or just false gynecomastia, you should notice some of these signs in the case of true gynecomastia:

  • A circular or oval-shaped, palpable lump or mass located directly behind or around the nipple and areola. It may be hard, rubbery, or firm to the touch when touched or pressed. 
  • Feeling pain when touching the breast or nipple, especially in teenagers. 
  • The enlargement is mainly around the nipple and may affect one or both breasts, and sometimes the enlargement is uneven between the breasts.
  • Weight loss reduces breast size somewhat, but the hard glandular mass will remain.

Does gynecomastia go away with exercise?

The answer to this question depends on the type of gynecomastia. If your false gynecomastia is the result of fat accumulation, a combination of a healthy weight-loss diet and regular exercise can lead to a noticeable improvement or even the disappearance of false gynecomastia.

But in the case of true gynecomastia, exercise alone cannot eliminate it. Rather, it requires treating the main cause of gynecomastia, as exercise may reduce the size of gynecomastia and make its appearance less noticeable, but it will not remove the enlarged glandular tissue.

Medical sources

This information was based on:

mayo clinic

ncbi.nlm.nih

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